Answers are given by:
Univ. Prof. Bogdan MARINESCU – 1 MD., Ph.D., Ofelia GOIDESCU1 MD.,
Violeta NICULAE-PORUMBESCU – 2 Principal Nurse
1. Department of Infertility, Clinical Hospital of Obstetrics- Gynecology “Prof. Dr. Panait Sîrbu”, Giulești Maternity Hospital,
2. Medical Centre for Obstetrics-Gynaecology and Sexology, Romania

Question No.1: What is the limit of male procreation?
A: Spermatogenesis, as well as testosterone secretion, is present throughout a male’s lifespan, which, theoretically, creates the premises for procreation. There are published cases of men aged 90-92 who fall into this category.
In reality, with age, the pathology of the sex chromosomes appears, such as the chromo- somal abnormalities, in addition to the structural ones of the sperm cell, as well as forms of associated pathology, autosomal dominantly transmitted diseases and concomitant pathologies.
In general, the probability of generating a pregnancy decreases especially after the male’s age of 50, the phenomenon being more obvious in the elderly male (after 65 years).
Thus, the existence of chromosomal abnormalities decreases the quality of sperm, with age. To these is added the hypospermia, which is also produced by androgen deficiency.

Question No.2: How can it be explained that some women have an abundant secretion of cervical fluid?
A: The clear, transparent liquid secretion identified in the cervix is called “cervical mucus” and is hormonally determined. Sometimes, the cervical mucus is produced abundantly, right at the time of ovulation, being a specific sign for this. After ovulation, the cervical secretion diminishes.

Question No.3: Does being “RT-PCR negative” or “SARS-CoV-2 antigen-negative” means that you are not infected with SARS-CoV-2?
A: Unfortunately, the molecular detection and viral antigens techniques only provide an image of a “momentary” status of your health.
If the result is negative for the identification of SARS-CoV-2 at the time of testing, it will miss the early stage of this infection (in which the virus does not replicate enough to be detected) and, of course, will not allow any subsequent infection to be detected, after testing.
For better accuracy of the results, it would be ideal to perform a detection test as follows:

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