Cervix uteri histogenesis defect- cause of sexual dysfunctions – Case report and review of specialty literature- DOI:10.37072/JCS.2021.04.01

Vasile NIȚESCU
Medical Centre for Obstetrics-Gynaecology and Sexology, Romania

Abstract
The defect in the shape of the cervix called “disruption” is caused by an extrinsic action, which, from an embryological point of view, interferes with the normal initial development of the uterus. Dysplasia occurs as a defect in histogenesis, usually due to the action of teratogenic factors.
In the presented clinical case, we are discussing about the disorganization of an organ part, in which the uterine fundus and the uterine body are normal and the cervix and isthmus of the uteri- ne body, respectively their left edge is transformed into a thin and elastic cystic wall, thus changing the morphophysiology of the local structure. In addition to the above-mentioned pathology, the patient also presented with incomplete longitudinal vaginal septum.
All these determined, in addition to the morphological changes, a clinical symptomatology, related to complex sexual dysfunction.
The presence of a paravaginal cyst in the left side of the cervix and uterine isthmus, formed by the effect of tissue disorganization during organogenesis, is not included in the types of congenital uterine abnormalities presented in the literature as utero-vaginal malformations that, according to Berek and Novak, occur in 0.16% of women.

Keywords:
histogenesis, disruption, dysplasia, sexual dysmorphism, sexual dysfunction, dyspareunia