The incidence of penile cancer – Correspondence

*Florin BACANU MD, Ph.D., Medical Oncology Senior Specialist,
Member of the National Society of Medical Oncology in Romania


  1. How to explain the fact that genital neoplasms in women (affecting the cervix, vagina or vulva) are much more common (incidence of 25 per 100,000 in Romania com- pared to 10/100,000 women worldwide, ranking second after breast cancer), while penile cancer is very rare (representing less than 1% of man’s malignancies)?
    HPV infection, cancer, uterine cervix, penis
    Papilloma virus (HPV) infection is involved 100% in the etiology of genital neoplasms in women and, respectively, 40% in the determinism of penis cancer. As HPV infec- tion is a sexually transmitted disease, a higher incidence of penile cancer would be expected.

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