Recto-sigmoid tumor pathology and disorders of normal sexual intercourse- Points of view DOI:10.37072/JCS.2020.03.02

1* Alexandru RUNCANU MD, PhD. , 2* Valentin NIȚESCU MD

1. Surgery Clinic-Emergency Clinical Hospital Bucharest “Floreasca”, Romania
2. Surgery Clinic – Louis Pasteur Hospital, Colmar, France

Abstract:
Malignant tumors have a great histopathological diversity (adenocarcinomas, carcinoid tumors, lymphomas, and sarcomas – the four major histopathological types), which generate localization, clinical presentation, prognosis, and treatment particularities.
In terms of oncological pathology, colorectal cancer is one of the most common types of malignancy in both sexes, accounting for 10% of all new cases diagnosed worldwide.
In men, the incidence is in third place, with an estimated 746,000 new cases per year, respectively 614,000 in women, in which it ranks second. In the global mortality hierarchy, colorectal cancer ranks fourth, with an estimated 649,000 deaths per year (1).
The incidence and mortality of this digestive neoplasm increase with age, more than 90% of newly diagnosed cases and, respectively, over 94% of deaths occur in people aged over 50 years.
The occurrence of colorectal malignancies in patients under the age of 40 is extremely rare, except for individuals with a genetic predisposition and those with acquired predisposing pathologies, such as chronic inflammatory bowel disease (2).
Colorectal cancer is a heterogeneous genetic pathology, in which the major feature is represented by genomic instability. Despite advances in understanding the tumor genome, colorectal cancer continues to rank second worldwide in mortality, due to the potential for metastasis and resistance to therapy. The involvement of molecular mechanisms in the formation of adenomas, with their possible transformation into carcinomas, and later into metastatic cancer, tends to be used for new therapeutic concepts (2).
Finally, the surgery of recto-sigmoid tumor pathology, through extensive pelvic interventions, resulting in significant organ and vascular-nervous lesions produced intraoperatively, is responsible for the appearance of sexual dysfunctions in men, especially of the erection one.
Keywords: tumor, colon, surgical dissection, neurovascular lesions, sexual dysfunction

Correspondence: 1* A.Runcanu University Assistant, MD, Ph.D., 46 Doamna Oltea Street, District 2, Bucharest, 2**Nițescu Valentin MD, E-mail: valentin_nitescu@yahoo.com